Vitamin D Status in Umbilical Cord Blood Related to Neonatal Birth Weight

Elly, Nur and Djuwita, Ratna (2019) Vitamin D Status in Umbilical Cord Blood Related to Neonatal Birth Weight. Indian Journal of Public Health Research & Development, 10 (5). pp. 527-531. ISSN 0976-5506

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Abstract

Introduction: Birth weight is an important determinant of infant’s survival and future development. Insufficient supply of vitamin D during fetal growth can affect birth outcomes. Objective: This study aimed to analyze relation of vitamin D status with neonatal birth weight. Method: This study used across-sectional design on 144 pregnant women and their infants that met inclusion criteria. Umbilical cord blood 25-hydroxyvitamin D [25(OH)D] was examined by Electro Chemiluminescence Immuno Assay method. Analysis used multiple linear regression. results: The mean concentration of 25(OH) D was 27.6 ng/mL and only 37.5% neonates had adequate vitamin D. The average birth weight was 3090.6 gr. After being controlled by maternal weight gain during pregnancy and energy intake, the mean birth weight was significantly 166.5 gr smaller in neonates with vitamin D deficiency (p<0.05). conclusion: Vitamin D status is related to neonatal birth weight. Efforts to increase vitamin D intake in pregnant women are necessary to improve fetal vitamin D status followed by exposure to sunlight.

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