Analysis of Differences in Levels of Blood Urea Nitrogen (Bun) and Glomerular Filtration Rate (Gfr) in Type 2 Diabetes Mellitus Patients with Chronic Ridal Failure and Hypertension

Susiwati, Susiwati and Nindita, Yora and Muslim, Zamharira and Sahidan, Sahidan (2023) Analysis of Differences in Levels of Blood Urea Nitrogen (Bun) and Glomerular Filtration Rate (Gfr) in Type 2 Diabetes Mellitus Patients with Chronic Ridal Failure and Hypertension. Star Shine Medical Journal, 3 (1). pp. 118-126. ISSN 2797-1502

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Abstract

Diabetes mellitus and its complications are a major threat to health status and are a heavyeconomic burden for individuals and society. Inconsistent and poorly managed diabetes care can lead to serious complications such as chronic kidney failure and hypertension. Decreased kidney function can be seen from a decrease in the glomerular filtration rate (GFR) and will be followed by an increase in blood urea nitrogen (BUN) levels. This study aims to measure differences in BUN and GFR levels in patients with type 2 diabetes mellitus who experience chronic kidney failure and hypertension. The study was conducted on 45 samples from 150 patient populations at M. Yunus Hospital Bengkulu City in 2022. Data were collected by taking venous blood samples. The blood sample is then checked for BUN and GFR levels in the laboratory. The data were analyzed using the paired sample T test for the paired sample, followed by the Independent T-test for the unpaired sample using the SPSS program. The results showed that the sig value (0.613) > 0.05 for the BUN level, and the sig value (0.554) > 0.05 for the GFR level. The conclusions of the study were: (1) there was no difference in the average bun levels of DM2 patients with CKD and hypertensive patients with CKD and (2) there was no difference in the average GFR of DM2 patients with CKD and hypertensive patients with CKD. Suggestions that can be put forward are that an early examination is needed if there are complaints that lead to urinary system disorders.

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