Comparative Study : Formula Praktis Estimasi Laju Filtrasi Glomerulus (LFG) dengan Biomarker Kreatinin Serum

Irawan, Putra Adi and Farizal, Jon and Febriyanto, Tedy (2019) Comparative Study : Formula Praktis Estimasi Laju Filtrasi Glomerulus (LFG) dengan Biomarker Kreatinin Serum. Jurnal Media Kesehatan, 12 (2). pp. 82-89. ISSN 2654-5705

	Text Artikel Comparative Study Formula Praktis Estimasi Laju Filtrasi Glomerulus (LFG) dengan Biomarker Kreatinin Serum.pdf Download (442kB)
	Text Peer Review Comparative Study Formula Praktis Estimasi Laju Filtrasi Glomerulus (LFG) dengan Biomarker Kreatinin Serum.pdf Download (58kB)
	Text Similarity Comparative Study Formula Praktis Estimasi Laju Filtrasi Glomerulus (LFG) dengan Biomarker Kreatinin Serum.pdf Download (26kB)
	Text Similarity-comparative study formula praktis estimasi laju filtrasi glomerulus(lfg) dengan biomarker kreatinin serum.pdf Download (26kB)

Abstract

Background: Estimation GFR is complicated to take a relatively long time, so it takes a practical and efficient method with accurate results as well. Indonesia is a country with moderately high chronic kidney disease patients. Riskesdas Data Ministry of Health 2013-2018 reported patients with kidney failure age ≥ 15 years of increasing each year. It takes several laboratory tests to give a proper picture of kidney health including: LFG. There are several formulas that have been researched earlier by experts including: Formula Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI), The isotope dilution mass spectrometry (ID-MS) Traceable Modification of Diet in Renal Disease (MDRD) , and Modification of Diet in Renal Disease (MDRD) 4 Variable. Objectives: Know the comparison of LFG estimates based on the formula CKD-EPI, ID-MS Traceable MDRD, and MDRD 4 Variable. Methods: Data used in research studies such as serum creatinine and subject age are obtained from secondary Data as much as 30 people. The GFR values are calculated with the CKD-EPI formula, ID-MS Traceable MDRD, and MDRD 4 Variable. Result: Average value of ± SD (n = 30) LFG based on the CKD-EPI formula is 71,36 ± 8.77 with the vulnerable value of GFR = 50,70-89,34. 93.30% suffered mild (60-89) and 6.70% Moderate damage (59-30). The average value of ± SD (n = 30) GFR based on the formula of the ID-MS Traceable MDRD is 64,79 ± 6,59 with vulnerable value of GFR = 48,48-78,40. 83.30% suffered mild (60-89) and 16.70% Moderate damage (59-30). Average value of ± SD (n = 30) GFR based on the MDRD 4 Variable formula is 68,86 ± 7,00 with vulnerable value GFR = 51,53-83,33. 93.30% suffered mild (60-89) and 6.70% Moderate damage (59-30). Conclusion: The use of three (3) such formulas can be used to estimate GFR. Nevertheless, the formula CKD-EPI or MDRD 4 variables are recommended.

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