Virulence of Candida Albicans in Patients with Diabetes Mellitus

Sunita, Sunita (2021) Virulence of Candida Albicans in Patients with Diabetes Mellitus. Star Shine Medical Journal, 1 (2). pp. 22-29. ISSN 2797-1502

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Abstract

Diabetes Mellitus is a predisposing factor for oral candidiasis. People with diabetes who are not well controlled, it can lead to a decrease in salivary flow rate, a decrease in salivary pH and an increase in salivary glucose levels, reduced salivary flow can increase the risk of developing lesions on the oral mucosa so that it can encourage the growth and colonization of Candida so that the oral mucosa with Diabetes Mellitus found Candida albicans. The objective of this research was to determine the virulence of Candida albicans with Diabetes Mellitus. This research was conducted using a descriptive survey design. The number of samples were 32 patients of diabetes mellitus in Puskesmas Padang Serai Kota Bengkulu, which taken by total sampling. Samples were examined macroscopically using Sabouraud Dextrose Agar media and microscopic examination using Potassium Hydroxide. The results showed that 17 respondents (53.1%) were positive for Candida albicans on the oral mucosa swab and 15 respondents (46.9%) were negative for Candida albicans on the oral mucosa swab. This percentage value indicates that most of the oral mucosal swab samples with diabetes mellitus have Candida albicans. It is recommended to keep blood sugar levels under control and maintain oral hygiene such as cleaning the mouth after eating in the morning and going to bed at night, and consuming foods containing lots of water.

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